I-FT3 kanye ne-FT4 yizifinyezo zesiNgisi ze-serum free triiodothyronine kanye ne-serum free thyroxine, ngokulandelanayo.
I-FT3 ne-FT4 yizinkomba ezibucayi kakhulu zokuxilongwa kwe-hyperthyroidism.
Ngenxa yokuthi okuqukethwe kwabo akuthintwa i-globulin ebopha i-thyroid, banenani elibalulekile lokusebenza ekuxilongweni kwe-hyperthyroidism ne-hypothyroidism, ukuhlolwa kobunzima besifo, nokuqapha imiphumela yokwelapha.
Ukunqunywa kwamazinga e-serum noma e-plasma ye-Triiodothyronine (T3) kuqashelwa njengesilinganiso esibalulekile ekuhloleni ukusebenza kwegilo.Imiphumela yayo ezicutshini eziqondiwe cishe inamandla aphindwe kane kunalawo e-T4.I-T3 yamahhala (FT3) iyifomu elingaboshiwe nelisebenza ngokwebhayoloji, elimele kuphela u-0.2–0.4 % wesamba se-T3.
Ukunqunywa kwe-T3 yamahhala kunenzuzo yokuzimela ngaphandle kwezinguquko ekugxilweni nasekubopheni izakhiwo zamaprotheni abophezelayo;Ngakho-ke i-T3 yamahhala iyithuluzi eliwusizo ekuxilongeni okujwayelekile komtholampilo ukuze kuhlolwe isimo segilo.Izilinganiso zamahhala ze-T3 zisekela ukuxilongwa okuhlukile kokuphazamiseka kwe-thyroid, kuyadingeka ukuze kuhlukaniswe izinhlobo ezahlukene ze-hyperthyroidism, nokuhlonza iziguli ezine-T3 thyrotoxicosis.
Ukunqunywa kwamazinga e-serum noma e-plasma ye-Thyroxine (T4) kubonwa njengesilinganiso esibalulekile ekuhloleni ukusebenza kwegilo.I-Thyroxine (T4) ingenye yamahomoni amabili amakhulu akhiqizwa indlala yegilo (enye ibizwa nge-triiodothyronine, noma i-T3), i-T4 ne-T3 ilawulwa uhlelo olubucayi lwempendulo olubandakanya i-hypothalamus kanye ne-pituitary gland.
I-T4 yamahhala ikalwa kanye ne-TSH lapho kusolwa ukuphazamiseka kokusebenza kwegilo.Ukuzimisela kwe-fT4 nakho kufanelekile ukuqapha ukwelashwa kwe-thyrosuppressive.Ukunqunywa kwe-T4 yamahhala kunenzuzo yokuzimela ngokuzimela ekushintsheni kokugxila kanye nezakhiwo ezibophezelayo zamaprotheni abophayo;
Okuqukethwe kwe-FT3 kubaluleke kakhulu ekuxilongeni okuhlukile kokuthi umsebenzi wegilo ujwayelekile, i-hyperthyroid noma i-hypothyroid.Izwela kakhulu ekuxilongweni kwe-hyperthyroidism futhi iyinkomba ethile yokuxilongwa kwe-T3 hyperthyroidism.
Ukunqunywa kwe-FT4 kuyingxenye ebalulekile yokuxilongwa okujwayelekile komtholampilo futhi kungasetshenziswa njengendlela yokuqapha yokwelapha i-thyroid suppression.Uma kusolwa ukungasebenzi kahle kwegilo, i-FT4 ne-TSH kuvame ukulinganiswa ndawonye.
Isikhathi sokuthumela: Nov-12-2021